Dual Color SRS with deltaEmerald

Dual Color SRS with deltaEmerald

Dual Color Stimulated Raman Scattering


Introduction

The new deltaEmerald allows simultaneous SRS imaging of two vibrational bands with its revolutionary dual color SRS (DC-SRS) scheme. It is aimed at users at the forefront of SRS microscopy, giving the best signal-to-noise performance and the capability of background subtraction as well as simultaneous imaging of two vibrational bands.

Two Stokes pulses, separated by 85 cm-1 and modulated at different frequencies are overlapped with the tunable Pump pulse.

The pulse length of about 1 ps, 10 cm-1 … 15 cm-1 bandwidth and several 100 mW output power in each beam are ideal parameters for Coherent Raman imaging.

The pulses of all three beams are shot noise limited due to solid state laser design and proven OPO technology. The shot noise limit of -162 dBc/Hz above 1 MHz (limited by the noise measurement setup with 4.8 mA) allows for fast image acquisition and superior signal-to-noise ratio.

Fully automated tuning, power control and temporal and spatial overlap of all three beams are given.

Additionally a ~100 fs output at 1030 nm is provided for efficient SHG and two-photon imaging.

 

For more details regarding Coherent Raman Microscopy, please look here.


Virtual Histology (Colon)
Diverse applications

At a Glance

  • Innovative SRS scheme for simultaneous excitation of two vibrational bands
  • Tunable Pump and both Stokes pulses are spatially and temporally overlapped
  • Spectral distance of Stokes beams 85 cm-1
  • Proven OPO technology with shot noise limited performance with -162 dBc/Hz above 1 MHz
  • Additional femtosecond output at 1030 nm beam for optimum SHG and TPF excitation

Applications

  • Simultaneous imaging of CH2 & CH3 for nondestructive and fast Coherent Raman histology. The 85 cm-1 energy difference is chosen to address CH2 & CH3 with 2845 cm-1 and 2930 cm-1 at their peak position.
  • Background removal of non-resonant artefacts, especially important for weak signals in the fingerprint region
  • Cream spreading quantification, Drug penetration, Metabolic imaging, Microplastics discrimination, Plant imaging, Cell imaging, Fingerprint imaging, etc.

Specifications

Applications

  
Laser sourcedeltaEmerald
   Wavelength Stokes 11034 nm
   Wavelength Stokes 21025 nm
   Wavelength Pump (OPO Signal)740 nm … 990 nm
   ∆v Pump - Stokes350 cm-1 … 3800 cm-1
   Power Stokes 1> 300 mW (unmodulated), > 150 mW modulated (20 MHz)
   Power Stokes 2> 300 mW (unmodulated), > 150 mW modulated (20 MHz)
   Power Pump (OPO Signal)> 400 mW at 800 nm
   Spectral bandwidth Pump and Stokes beams10 cm-1 … 15 cm-1
   Pulse width1 ps
   Repetition rate80 MHz
   NoiseShot noise limited (-162 dBc/Hz) > 1 MHz for Pump and Stokes
Beam parameters
   Pointing stability< 100 µrad per 100 nm
   M²< 1.2 for Pump and Stokes
   Ellipticity< 20%
   PolarizationLinear; horizontal > 100 : 1
   Beam divergence0.9 mrad ± 0.2 mrad at 800 nm and Stokes
   Beam waist diameter1.3 mm ± 0.2 mm at 800 nm, 1.7 mm ± 0.2 mm for Stokes
Additional femtosecond output
   Wavelength1030 nm ± 3 nm
   Power300 mW
   Pulse width< 200 fs
   Beam divergence< 1.5 mrad
Features
   Integrated modulator for StokesBuilt-in EOMs with resonant fixed frequency of 20 MHz and 13 MHz
   Power attenuatorsIntegrated for Pump and Stokes, independent for each beam
   Delay managementAutomated compensation for microscope dispersion
   Remote controlEthernet and Software interface TCP/IP
  • Simultaneous imaging of CH2 & CH3 for nondestructive and fast Coherent Raman histology. The 85 cm-1 energy difference is chosen to address CH2 & CH3 with 2845 cm-1 and 2930 cm-1 at their peak position.
  • Background removal of non-resonant artefacts, especially important for weak signals in the fingerprint region
  • Cream spreading quantification, Drug penetration, Metabolic imaging, Microplastics discrimination, Plant imaging, Cell imaging, Fingerprint imaging, etc.

Datasheets & Brochures

APE deltaEmerald rev.1.0.0 (pdf / english)


Contact Us







I consent to APE's data safety & privacy conditions.

You need to consent to APE's data safety & privacy conditions before the "send" button is active. You find the data safety & privacy conditions here.

or

Email & Phone Contacts

APE has distributors around the world to give you the best support. Choose a country to find your local sales contact:

APE Angewandte Physik & Elektronik GmbH
Plauener Strasse 163-165 | Haus N
13053 Berlin, Germany

Phone: +49 30 986 011-30
Fax: +49 30 986011333

Sales: sales@ape-berlin.de
Support: service@ape-berlin.de

Coherent Scientific pty. Ltd.
Hilton SA 5033, South Australia

Phone: +61 8 8150 5200
Email: sales@coherent.com.au
Website: www.coherent.com.au

PulsePower Technology Ltd.
Beijing, Haidan District
China 100090

Phone:+86 10 62565117
Email: mlu@pulsepower.cn
Website: www.pulsepower.cn



Pinnacle Scientific Cooperation
Hangzhou, Jianggan District
China 310020

Phone: +86 571 88225151
Email: sales@psci.cn
Website: www.psci.cn

OptiXs
199 00 Praha 9, Česko

Phone: +420 212 247 293
Email: info@optixs.cz
Website: www.optixs.cz

Gammadata Instrument AB
750 02 Uppsala
Sweden

Phone: +46 18 56 68 35
Email: sales@gammadata.se
Website: www.gammadata.se

Optoprim
F 92170 Vanves, France

Phone: +33 1 419 061 80
Email: info@optoprim.com
Website: www.optoprim.com

Laser Sciences Services Pvt. Ltd.

Phone: +91 2778 1673
Email: sales@laserscience.in
Website: www.laserscience.co.in/

Photonic Solutions Ltd.
Edinburgh, UK

Phone: +44 131 664 8122
Email: sales@photonicsolutions.co.uk or
Email: ben.agate@photonicsolutions.co.uk
Website: www.photonicsolutions.co.uk

Ammo Engineering Ltd.
Petach Tikva 49517, Israel

Phone: +972 3 9239 666
Email: ammo1@ammo.co.il
Website: www.ammo.co.il

Optoprim Srl.

UFFICIO DI MONZA
Via Rota, 37
20900 Monza (MB)

Phone: +39 039 834977
Email: info@optoprim.it
Website: www.optoprim.it

UFFICIO DI ROMA
Via Monte Giberto, 15
00138 Roma

Phone: +39 06 87657838
Email: info@optoprim.it
Website: www.optoprim.it

Phototechnica Corporation
Saitama 336-0017, Japan

Phone: +81 48 871 0067
Email: voc@phototechnica.co.jp
Website: www.phototechnica.co.jp

RayVis
Seoul 137-862, Korea

Phone: +82 2 3461 1103
Email: sales@rayvis.co.kr
Website: www.rayvis.co.kr

STARK SCIENTIFIC S.A. DE C.V.
Guty Cardenas 147, Guadalupe Inn
Ciudad de Mexico, C.P. 01020, Mexico

Main Contact: Vicente Garcia Gomez

Phone: +52 555 401 8254
Email: sales@starkscientific.com

Eurotek International
02-668 Warsaw, Poland

Phone: +48 22 843 79 40
Email: eurotek@eurotek.com.pl
Website: www.eurotek.com

Innova Scientific S.L.
28290 Las Rozas de Madrid, Espana

Phone: +34 91 7105650
Email: info@innovasci.com
Website: www.innovasci.com

AceXon Technologies Pte. Ltd.
Singapore 658065

Phone: +65 6565 7300
Email: sales@acexon.com
Website: www.acexontech.com

Innova Scientific S.L.
28290 Las Rozas de Madrid
Espana

Phone: +34 91 7105650
Email: info@innovasci.com
Website: www.innovasci.com

SuperbIN Company Ltd.
5F., No. 41, Ln. 15, Sec. 6, Minquan E. Rd., Taipei 114
Taiwan, R.O.C.

Phone: +886-2-2793-0866
Fax: +886-2-2793-0855
Email: info@superbin.com.tw
Website: www.superbin.com.tw

Photonic Solutions Ltd.
Edinburgh
UK

Phone: +44 131 664 8122
Email: sales@photonicsolutions.co.uk or
Email: ben.agate@photonicsolutions.co.uk
Website: www.photonicsolutions.co.uk

APE Applied Physics & Electronics, Inc.
Vancouver | WA | USA

Phone: +1 888 690 3250
Sales: sales@ape-america.com
Support: service@ape-america.com


Dual Color Stimulated Raman Scattering with deltaEmerald full compatible with DC-CRS microscope by Lightcore Technologies.